BiohacksAI/Mechanism Hypothesis/alpha-Linolenic Acid

alpha-Linolenic Acid — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6CYP2C9NR1I2CYTOCHROMETHRBCYP3A4NFE2L2CHAINGLI3TP53NR3C1EUCHROMATICPPARGVDRPTGS1MAPTALDEHYDEPOLKHSPB1GLSPOLIALOX15POLHKAT2APPARAALOX15BUSP17L5USP28USP30SIRT5ATG4BFFAR1WRNOTUD3USP8FFAR4USP10UCHL1USP7CATHEPSINID4FREE

43 known targets mapped from PubChem bioassay data

Pathway Context

Deubiquitination10 targets overlapping

Ub-specific processing proteases8 targets overlapping

SUMOylation7 targets overlapping

Uncovered Pathway Targets

145 total

ADRB2ADRM1ARARRB1BAP1BARD1BRCA1CCNA1CDC25ACDK1+135 more…

Genes present in the top pathway union that alpha-Linolenic Acid does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 47 targets covered · evidence score 44.2

score 12,915.377

ADRM1ARESR1HIF1ANLRP3PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7+35

Reserpine

#2 gap-filler · 17 targets covered · evidence score 41.7

score 4,338.975

ADRB2ARESR1PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1PSMB2+5

665 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.