Amisulpride — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2D6DRD35-HYDROXYTRYPTAMINEHTR2ADRD2ADRA2AHTR2BADRA2CADRA2BACHEHTR7
11 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)8 targets overlapping
Amine ligand-binding receptors8 targets overlapping
G alpha (i) signalling events4 targets overlapping
Uncovered Pathway Targets
315 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3AGTR1AGTR2+305 more…
Genes present in the top pathway union that Amisulpride does not directly modulate.
Top Stack Candidates
Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on
score 9,875.613#1 gap-filler · 34 targets covered · evidence score 44.3
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3DRD4TSHRCREB1GRK2TAS2R1TAS2R10+22
Astemizole Antihistamine drug now withdrawn from
score 6,028.376#2 gap-filler · 28 targets covered · evidence score 48.7
ADRA1AADRB2APLNRAVPR1ACHRM1CHRM2CHRM3DRD1DRD4GALR2GHSRHRH1+16
843 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.