BiohacksAI/Mechanism Hypothesis/Androsterone

Androsterone — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

ARCYP2C9NR1I2ESR1ESRRACHAINGLI3PGRRORCSHBGSERPINA6GPBAR1NLRP3TARDBPGABRA1GABRA2GABRA3GABRA4GABRB2GABRB3GABRG2GABRA5GABRA6GABRB1GABRDGABREGABRG1GABRG3GABRPGABAHSD17B3

31 known targets mapped from PubChem bioassay data

Pathway Context

Neuronal System11 targets overlapping

Transmission across Chemical Synapses11 targets overlapping

Neurotransmitter receptors and postsynaptic signal transmission11 targets overlapping

Uncovered Pathway Targets

251 total

ABATABCC8ABCC9ACHEADCY9ALDH2ALDH5A1BCHECACNA1BCACNA2D1+241 more…

Genes present in the top pathway union that Androsterone does not directly modulate.

Top Stack Candidates

Sorafenib

#1 gap-filler · 41 targets covered · evidence score 44.4

score 10,774.624

CAMK2BMAOAMAPK1MAPK3NTRK3RPS6KA1RPS6KA6SLC6A3SRCAXLBRAFCDK5+29

Crizotinib

#2 gap-filler · 34 targets covered · evidence score 46.7

score 9,438.713

CAMKK2CASKKCNH2NTRK3PRKAA1SLC6A3SLC6A4SRCALKAXLFERFES+22

581 more candidates · full stack optimisation locked

Enter your API token to unlock the complete analysis.

BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.