Antimycin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
TDP1NFE2L2SYKTYROSINE-PROTEINCHAINTP53YAP1ABCC2RAPGEF4SLCO1B1SLCO1B3MITOGEN-ACTIVATEDPRKAA2PRKAA1PRKAB1PRKAB2PRKAG1PRKAG2PRKAG3PARL
20 known targets mapped from PubChem bioassay data
Pathway Context
Regulation of T cell activation by CD28 family9 targets overlapping
Co-inhibition by PD-19 targets overlapping
Regulation of PD-L1(CD274) expression9 targets overlapping
Uncovered Pathway Targets
151 totalADRM1AGO2AKT3ASH2LBRD4CDC42CDK4COPS5CREBBPCSK+141 more…
Genes present in the top pathway union that Antimycin does not directly modulate.
Top Stack Candidates
Bortezomib
score 11,861.632#1 gap-filler · 39 targets covered · evidence score 44.2
ADRM1EPAS1HIF1ANFKB1NFKB2PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7+27
Quercetin
score 5,230.918#2 gap-filler · 22 targets covered · evidence score 43.4
CSNK2A1CSNK2A2CSNK2BEZH2GSK3BHIF1ANEK2NFKB1NFKB2PIK3CGPIK3R1PSMB5+10
300 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.