BiohacksAI/Mechanism Hypothesis/Arachidonic Acid

Arachidonic Acid — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

PPARGVDRMAPTRXRAPTGS2POLKPPARDGFERRAPGEF4ALOX15HPGDRAPGEF3SLCO1B1USP1CACNA1CKAT2APLA2G7SLCO1B3PPARATRPC6TRPM2HSPD1HSPE1OXTRKCNK3KCNK2KCNJ5KCNK10FABP5KCNJ4FABP4PRKCZKCND2KCNK4KCNK18

35 known targets mapped from PubChem bioassay data

Pathway Context

Muscle contraction7 targets overlapping

Cardiac conduction7 targets overlapping

Neuronal System6 targets overlapping

Uncovered Pathway Targets

184 total

ABCC9ALDH2ANXA2ASPHATP1A1ATP1A2ATP1A3ATP1A4ATP1B1ATP1B2+174 more…

Genes present in the top pathway union that Arachidonic Acid does not directly modulate.

Top Stack Candidates

Ondansetron

#1 gap-filler · 19 targets covered · evidence score 56.7

score 5,521.744

KCNH2ACHECHRNA4GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3+7

gamma-Aminobutyric Acid

#2 gap-filler · 19 targets covered · evidence score 43.1

score 4,929.67

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRG2+7

513 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.