butein — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
MUSPTGS1PTGS2POLKHDAC6ALOX12EPIDERMALAKR1B1ALOX5PHOSPHATIDYLINOSITOLBACE1
11 known targets mapped from PubChem bioassay data
Pathway Context
Fatty acid metabolism3 targets overlapping
Biosynthesis of DHA-derived SPMs3 targets overlapping
Biosynthesis of specialized proresolving mediators (SPMs)3 targets overlapping
Uncovered Pathway Targets
38 totalABCC1ACAD11AKR1C3ALOX15ALOX15BCBR1CPT2CYP1A1CYP1A2CYP1B1+28 more…
Genes present in the top pathway union that butein does not directly modulate.
Top Stack Candidates
Quercetin
score 2,592.28#1 gap-filler · 14 targets covered · evidence score 43.4
ABCC1ALOX15ALOX15BCYP1A1CYP1A2CYP1B1CYP2C19CYP2C8CYP2C9HPGDPON1PRKAA2+2
Apigenin 5,7,4'-trihydroxy-flavone,
score 1,627.186#2 gap-filler · 11 targets covered · evidence score 42.3
ABCC1ALOX15CYP1A1CYP1A2CYP1B1CYP2C19CYP2C9HPGDPPARDCYP2D6CYP3A4
664 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.