Cholic Acid — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
NR1H4ABCB11GPBAR1PLA2G1BG-PROTEIN
5 known targets mapped from PubChem bioassay data
Pathway Context
Metabolism of steroids2 targets overlapping
Bile acid and bile salt metabolism2 targets overlapping
Recycling of bile acids and salts2 targets overlapping
Uncovered Pathway Targets
40 totalABCC3AKR1C1AKR1C2AKR1C3AKR1C4ALBCARM1CREBBPCYP11B1CYP11B2+30 more…
Genes present in the top pathway union that Cholic Acid does not directly modulate.
Top Stack Candidates
Atorvastatin
score 1,953.858#1 gap-filler · 5 targets covered · evidence score 74.8
CYP19A1HMGCRSLCO1B1SLCO1B3SREBF2
Miconazole
score 1,212.123#2 gap-filler · 5 targets covered · evidence score 46.8
CYP17A1CYP19A1CYP51A1CYP8B1VDR
301 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.