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BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/Cimetidine

Cimetidine — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6ARCYP2C9CYTOCHROMECYP3A7MUSADRA1AHTR2APOLKHRH2HISTAMINEPDE4ASLC22A1SLC22A2SLC47A1SLC29A4ATP4AATP4B

19 known targets mapped from PubChem bioassay data

Pathway Context

Biological oxidations4 targets overlapping
Drug ADME4 targets overlapping
Phase I - Functionalization of compounds4 targets overlapping

Uncovered Pathway Targets

83 total
AADACAHCYAHRALDH1A1ALDH2AOC1ARNTCBR3CES1CES2+73 more…

Genes present in the top pathway union that Cimetidine does not directly modulate.

Top Stack Candidates

Quercetin

#1 gap-filler · 17 targets covered · evidence score 43.4

score 3,203.002
AHRCYP19A1CYP1A1CYP1A2CYP1B1CYP2C8CYP3A4HSP90AB1MAOANNMTRXRAABCB1+5
Ritonavir

#2 gap-filler · 10 targets covered · evidence score 53.4

score 2,756.323
CYP2B6CYP3A4CYP3A43CYP3A5CYP3A7-CYP3A51PUGT1A1ABCB1SLCO1B1SLCO1B3SLCO2B1

664 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.