BiohacksAI/Mechanism Hypothesis/Dequalinium

Dequalinium — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2D6TDP1CYP1A2CYP3A4SYKTYROSINE-PROTEINCHAINNSD2HISTONE-LYSINEKCNH2CHRM1DRD3ADRA1ADRD1HTR1AADRA2APTGS1SLC6A3ACHEPMP22SLC6A4MU-TYPESLC6A2CHRM2HIF1AADORA3NNMTPNMTGAMTGNMTHNMTCATECHOLRGS4MTORFEN1PDE4AHRH3CGASAICDAKCNN1KCNN2CNGA2KCNN3CNGA1

44 known targets mapped from PubChem bioassay data

Pathway Context

Class A/1 (Rhodopsin-like receptors)9 targets overlapping

Amine ligand-binding receptors8 targets overlapping

Neuronal System6 targets overlapping

Uncovered Pathway Targets

382 total

ADORA2BADRA1BADRA1DADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AGTR2+372 more…

Genes present in the top pathway union that Dequalinium does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 34 targets covered · evidence score 44.2

score 10,656.697

CREB1ADRM1PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1PSMB2PSMB3+22

Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on

#2 gap-filler · 35 targets covered · evidence score 44.3

score 10,095.634

ADRA1BADRA1DADRB1ADRB2ADRB3DRD2DRD4TSHRCREB1GRK2TAS2R1TAS2R10+23

809 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.