BiohacksAI/Mechanism Hypothesis/Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of
Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2D6CYTOCHROMERATTUS5-HYDROXYTRYPTAMINEADRA1AHTR2BSLC6A4MU-TYPEKAPPA-TYPESODIUM-DEPENDENTSCN2ASIGMAR1SCN3ASCN1AGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BTACR1MAS-RELATEDCYP2D2
24 known targets mapped from PubChem bioassay data
Pathway Context
Neuronal System5 targets overlapping
Transmission across Chemical Synapses5 targets overlapping
Neurotransmitter receptors and postsynaptic signal transmission4 targets overlapping
Uncovered Pathway Targets
136 totalABATABCC8ABCC9ACHEADCY9ALDH2ALDH5A1BCHECACNA1BCACNA2D1+126 more…
Genes present in the top pathway union that Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of does not directly modulate.
Top Stack Candidates
Ondansetron
score 5,521.744#1 gap-filler · 19 targets covered · evidence score 56.7
ACHECHRNA4GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRG2+7
gamma-Aminobutyric Acid
score 4,929.67#2 gap-filler · 19 targets covered · evidence score 43.1
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRG2+7
474 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.