Dihydroergocristine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARTDP1THRBRORCDRD1ADRB2APH1AAPH1BNCSTNPSEN1PSEN2PSENEN
12 known targets mapped from PubChem bioassay data
Pathway Context
Signaling by Receptor Tyrosine Kinases6 targets overlapping
Signaling by ERBB46 targets overlapping
Nuclear signaling by ERBB46 targets overlapping
Uncovered Pathway Targets
224 totalADAM10ADAM17AKT3ALKATP6V1B2AXLBRAFCDC37CDC42CDK5+214 more…
Genes present in the top pathway union that Dihydroergocristine does not directly modulate.
Top Stack Candidates
Bortezomib
score 13,836.471#1 gap-filler · 49 targets covered · evidence score 44.2
CMA1CREB1ESR1HDAC1HDAC2HDAC3HIF1AHSPB1PGRPLATADRM1ELANE+37
Sorafenib
score 10,762.063#2 gap-filler · 40 targets covered · evidence score 44.4
AXLBRAFCDK5CSKFGFR1FGFR2FGFR3FLT1FLT3FLT4FYNINSR+28
623 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.