BiohacksAI/Mechanism Hypothesis/dilazep

dilazep — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2C9NR1I2ESR1CYTOCHROMETDP1THRBCYP3A4CYP3A7NFE2L2SYKTYROSINE-PROTEINGLI3NSD2HISTONE-LYSINEKCNH2RARACHRM15-HYDROXYTRYPTAMINEATAD5PMP22SLC6A4CHRM3SCN2ASCN3ASCN1AHRH3SLC29A1SLC29A2

29 known targets mapped from PubChem bioassay data

Pathway Context

Biological oxidations4 targets overlapping

Drug ADME4 targets overlapping

Phase I - Functionalization of compounds4 targets overlapping

Uncovered Pathway Targets

83 total

AADACAHCYAHRALDH1A1ALDH2AOC1ARNTCBR3CES1CES2+73 more…

Genes present in the top pathway union that dilazep does not directly modulate.

Top Stack Candidates

Quercetin

#1 gap-filler · 16 targets covered · evidence score 43.4

score 3,101.941

AHRCYP19A1CYP1A1CYP1A2CYP1B1CYP2C8HSP90AB1MAOANNMTRXRAABCB1ABCC1+4

Ritonavir

#2 gap-filler · 10 targets covered · evidence score 53.4

score 2,736.614

CYP2B6CYP2D6CYP3A43CYP3A5CYP3A7-CYP3A51PUGT1A1ABCB1SLCO1B1SLCO1B3SLCO2B1

723 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.