B

BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/egcg

egcg — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19ARCYP2C9THRBCYP3A4GLI3ABCB1JUNSMAD3MAPTSMAD2HIF1AMITFBAZ2BPOLBNFKB1RGS4APPMTORMCL1SNCAGSK3BTTRAKR1B10CLK1CGASDNMT1DYRK1ACDK5PSMB5MAPK14PABPC1ALBRAD52BACE1HSPD1HSPE1ALPIEIF4HCDK5R1FYNMPIMETDYRK3CLK3STAT1CSNK1EDHFRDYRK2FASNPTGESTSTVCPCLK2CLK4DLDGALK1TPTEP2-CSNK1EDYRK1BTERTADAMTS4EP300KAT2BPGDADAMTS5DYRK4FUT7SERPINE1BADBCL2A1BCL2L10BCL2L2BIDFUT6GNAO1MAPKAPK5NADKPGAM1RGS7RGS8RPSASQLE

82 known targets mapped from PubChem bioassay data

Pathway Context

Signaling by Interleukins10 targets overlapping
Signaling by Receptor Tyrosine Kinases10 targets overlapping
Regulation of T cell activation by CD28 family10 targets overlapping

Uncovered Pathway Targets

301 total
ADRM1ALOX15ALOX5ANXA2BCL2L1BIRC5CA1CASP1CCL2CDC42+291 more…

Genes present in the top pathway union that egcg does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 50 targets covered · evidence score 44.2

score 13,953.115
ADRM1CA1CREB1CTSGIFNGNFKB2PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6+38
Sorafenib

#2 gap-filler · 46 targets covered · evidence score 44.4

score 11,857.784
CSF1RHCKIFNGIRAK1JAK3LCKLYNMAOAMAP2K1MAP3K7MAPK1MAPK11+34

820 more candidates · full stack optimisation locked

Enter your API token to unlock the complete analysis.

BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.