Ethylenethiourea — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19ESR1NFE2L2ESR2TSHRCHRM4PTBP1TAS2R38
8 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)2 targets overlapping
Nuclear Receptor transcription pathway2 targets overlapping
Signaling by Nuclear Receptors2 targets overlapping
Uncovered Pathway Targets
429 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2+419 more…
Genes present in the top pathway union that Ethylenethiourea does not directly modulate.
Top Stack Candidates
Bortezomib
score 13,115.828#1 gap-filler · 47 targets covered · evidence score 44.2
ARESRRANR1I2PGRPPARDRARACREB1HDAC1HDAC3HSPB1CMA1HDAC2+35
Sorafenib
score 12,263.069#2 gap-filler · 48 targets covered · evidence score 44.4
ADORA3HTR2BHTR2CHTR6HTR7MLNRMAPK1MAPK3SRCAXLBRAFCDK5+36
998 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.