BiohacksAI/Mechanism Hypothesis/gamma-Aminobutyric Acid

gamma-Aminobutyric Acid — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

RATTUSEUCHROMATICHDAC9HSF1GABRA1GABRA2GABRA3GABRA4GABRB2GABRB3GABRG2HDAC10GABRA5GABRA6GABRB1GABRDGABREGABRG1GABRG3GABRPHDAC11HDAC4HDAC5HDAC7GAMMA-AMINOBUTYRICPROTEINGABRQGABASLC6A1HISTONEGP6SLC6A6GABRR1GABRR2GABRR3SLC6A12GABBR1GABBR2SLC6A11SLC6A13

40 known targets mapped from PubChem bioassay data

Pathway Context

Neuronal System19 targets overlapping

Transmission across Chemical Synapses19 targets overlapping

Neurotransmitter receptors and postsynaptic signal transmission17 targets overlapping

Uncovered Pathway Targets

245 total

ABATABCC8ABCC9ACHEADCY9ALDH2ALDH5A1BCHECACNA1BCACNA2D1+235 more…

Genes present in the top pathway union that gamma-Aminobutyric Acid does not directly modulate.

Top Stack Candidates

Sorafenib

#1 gap-filler · 41 targets covered · evidence score 44.4

score 10,774.624

CAMK2BMAOAMAPK1MAPK3NTRK3RPS6KA1RPS6KA6SLC6A3SRCAXLBRAFCDK5+29

Crizotinib

#2 gap-filler · 34 targets covered · evidence score 46.7

score 9,438.713

CAMKK2CASKKCNH2NTRK3PRKAA1SLC6A3SLC6A4SRCALKAXLFERFES+22

720 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.