Glycine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19CYP2D6CYP2C9GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BOR51E2SLC6A5SLC6A9
13 known targets mapped from PubChem bioassay data
Pathway Context
Neuronal System4 targets overlapping
Transmission across Chemical Synapses4 targets overlapping
Neurotransmitter receptors and postsynaptic signal transmission4 targets overlapping
Uncovered Pathway Targets
137 totalABATABCC8ABCC9ACHEADCY9ALDH2ALDH5A1BCHECACNA1BCACNA2D1+127 more…
Genes present in the top pathway union that Glycine does not directly modulate.
Top Stack Candidates
Ondansetron
score 5,521.744#1 gap-filler · 19 targets covered · evidence score 56.7
ACHECHRNA4GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRG2+7
gamma-Aminobutyric Acid
score 4,929.67#2 gap-filler · 19 targets covered · evidence score 43.1
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRG2+7
482 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.