BiohacksAI/Mechanism Hypothesis/Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is
Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
TDP1CYP1A2CYP3A4CHAINRORCMUSNUCLEARTP53HTR2AADRA2AADRA2CADRA2BSLC6A2HTR2CALDEHYDEIL1BHIF1AYAP1HTR7HTR6MAOAABCG2GSK3BCLK1AMINEPHOSPHATIDYLINOSITOLDYRK1ACDK5CYCLIN-DEPENDENTNISCHCDK5R1DYRK3DUALCLK3CSNK1EDYRK2CYCLIN-A2ROCK1CLK2CLK4TPTEP2-CSNK1EMELKDYRK1BCASEINCSNK1DPIM3CYCLIN-T1DYRK4HASPINSMO
50 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)7 targets overlapping
Amine ligand-binding receptors7 targets overlapping
Hemostasis5 targets overlapping
Uncovered Pathway Targets
463 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3AGTR1AGTR2+453 more…
Genes present in the top pathway union that Harmine Alkaloid isolated from seeds of PEGANUM HARMALA; ZYGOPHYLLACEAE. It is identical to banisterine, or telepathine, from Banisteria caapi and is does not directly modulate.
Top Stack Candidates
Bortezomib
score 14,364.633#1 gap-filler · 51 targets covered · evidence score 44.2
F12HDAC1HDAC2IFNB1PLATSYKADRM1CA1CREB1CTSGIFNGNFKB1+39
Crizotinib
score 14,167.386#2 gap-filler · 52 targets covered · evidence score 46.7
ADORA3ADRA1AHRH2HTR2BNPY1RABL1CD74FGRFYNIFNB1LCKLYN+40
1002 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.