Indoramin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
RATTUSDRD3ADRA1ADRD1ADRA2AADRA2CADRA2BADRA1BADRA1D
9 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)8 targets overlapping
Amine ligand-binding receptors8 targets overlapping
Adrenoceptors6 targets overlapping
Uncovered Pathway Targets
315 totalADORA2BADORA3ADRB1ADRB2ADRB3AGTR1AGTR2APLNRAPPAVPR1A+305 more…
Genes present in the top pathway union that Indoramin does not directly modulate.
Top Stack Candidates
Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on
score 9,520.398#1 gap-filler · 32 targets covered · evidence score 44.3
ADRB1ADRB2ADRB3DRD2DRD4TSHRCREB1GRK2TAS2R1TAS2R10TAS2R13TAS2R14+20
Astemizole Antihistamine drug now withdrawn from
score 6,391.046#2 gap-filler · 30 targets covered · evidence score 48.7
ADRB2APLNRAVPR1ACHRM1CHRM2CHRM3DRD2DRD4GALR2GHSRHRH1HRH2+18
839 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.