BiohacksAI/Mechanism Hypothesis/Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of
Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARESR1TDP1CYP1A2THRBESRRASYKTYROSINE-PROTEINCHAINRATTUSNSD2RORCHISTONE-LYSINENUCLEARTP53HOMOIFNGPPARGPMP22STK33MDM2MDM4YAP1SNCASMN2ALBSMN1UGT2B7IMPDH1IMPDH2
30 known targets mapped from PubChem bioassay data
Pathway Context
SUMOylation5 targets overlapping
SUMO E3 ligases SUMOylate target proteins5 targets overlapping
Deubiquitination5 targets overlapping
Uncovered Pathway Targets
235 totalAURKAAURKBBIRC5BLMBRCA1CREBBPCTBP1DNMT1DNMT3BEIF2AK2+225 more…
Genes present in the top pathway union that Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of does not directly modulate.
Top Stack Candidates
Bortezomib
score 13,556.977#1 gap-filler · 51 targets covered · evidence score 44.2
HDAC1HDAC2MITFNFKB2NR1I2PARP1PGRRARARELAADRM1HIF1ANLRP3+39
Quercetin
score 8,836.227#2 gap-filler · 43 targets covered · evidence score 43.4
AURKBBLMNFKB2NR1I2NR3C1PGRRELARXRATOP1TOP2ACDK1HIF1A+31
930 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.