paxilline — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
EUCHROMATICGMNNMDM2MDM4BRCA1BARD1MCL1NPY1RTARDBPNPY2RMRGPRX1DDIT3BCL2L1ATP2A2ATP2A3
15 known targets mapped from PubChem bioassay data
Pathway Context
Cell Cycle5 targets overlapping
Deubiquitination4 targets overlapping
Cell Cycle Checkpoints4 targets overlapping
Uncovered Pathway Targets
224 totalABL1ADRM1AKT3ATMAURKAAURKBBIRC5BLMCCNA1CCNB1+214 more…
Genes present in the top pathway union that paxilline does not directly modulate.
Top Stack Candidates
Bortezomib
score 12,199.009#1 gap-filler · 43 targets covered · evidence score 44.2
ADRM1HDAC1HDAC8NSD2PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1+31
Quercetin
score 8,117.157#2 gap-filler · 37 targets covered · evidence score 43.4
ABL1AURKBBLMCDK1CSNK2A1CSNK2A2CSNK2BFEN1GSK3BHSP90AA1HSP90AB1MAPK14+25
674 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.