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BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/Phenylbutazone

Phenylbutazone — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6CYP2C9NR1I2ESR1CYTOCHROMEESRRACYP3A4CYP3A7RATTUSTP53EUCHROMATICESR2PTGS1PTGS2IFNB1HLA-BMCL1ITGA4ALBNAPRTFPR1

22 known targets mapped from PubChem bioassay data

Pathway Context

Biological oxidations5 targets overlapping
Drug ADME5 targets overlapping
Phase I - Functionalization of compounds5 targets overlapping

Uncovered Pathway Targets

82 total
AADACAHCYAHRALDH1A1ALDH2AOC1ARNTCBR3CES1CES2+72 more…

Genes present in the top pathway union that Phenylbutazone does not directly modulate.

Top Stack Candidates

Quercetin

#1 gap-filler · 16 targets covered · evidence score 43.4

score 3,101.941
AHRCYP19A1CYP1A1CYP1A2CYP1B1CYP2C8HSP90AB1MAOANNMTRXRAABCB1ABCC1+4
Ritonavir

#2 gap-filler · 9 targets covered · evidence score 53.4

score 2,631.977
CYP2B6CYP3A43CYP3A5CYP3A7-CYP3A51PUGT1A1ABCB1SLCO1B1SLCO1B3SLCO2B1

615 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.