phlorhizin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
AKR1B10SLC5A1SLC5A2SLC5A11SLC5A3
5 known targets mapped from PubChem bioassay data
Pathway Context
SLC-mediated transmembrane transport4 targets overlapping
Disorders of transmembrane transporters2 targets overlapping
SLC transporter disorders2 targets overlapping
Uncovered Pathway Targets
101 totalRUNX1SLC12A1SLC12A2SLC12A3SLC12A5SLC15A1SLC15A3SLC15A4SLC17A5SLC1A1+91 more…
Genes present in the top pathway union that phlorhizin does not directly modulate.
Top Stack Candidates
Bortezomib
score 10,360.47#1 gap-filler · 32 targets covered · evidence score 44.2
ADRM1PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1PSMB2PSMB3PSMB4+20
Reserpine
score 4,184.679#2 gap-filler · 15 targets covered · evidence score 41.7
ABCB11PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1PSMB2PSMB3PSMB4+3
355 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.