BiohacksAI/Mechanism Hypothesis/piceatannol

piceatannol — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

TDP1THRBESRRASYKTYROSINE-PROTEINCHAINNSD2MUSHISTONE-LYSINEEUCHROMATICCHRM1DRD1NTMT1ATAD5MAPTSTK33POLKCASP3NNMTPNMTGAMTGNMTHNMTCATECHOLHDAC6GFERPOLBGLSHSP90AA1RGS4CBX1ALOX12POLIMPHOSPH8FEN1POLHSENP8SMN2GPT2TTRHSP90AB1GSK3AALOX15BALOX5PIP4K2APIM1DYRK1APLGUSP17L5ABHD4LCKSENP6ALPIUSP28USP30SENP7PLAUPLAURMACROPHAGEFHHTRA1MATRIXOTUD3BAP1PI4K2ANAE1UBE2MGLO1GEMADAMTS4ADAMTS5ARSANEUTROPHIL

73 known targets mapped from PubChem bioassay data

Pathway Context

Deubiquitination7 targets overlapping

DNA Repair7 targets overlapping

Metabolism of amino acids and derivatives7 targets overlapping

Uncovered Pathway Targets

295 total

ADRB2ADRM1ARARRB1BARD1BRCA1CCNA1CDC25ACDK1CFTR+285 more…

Genes present in the top pathway union that piceatannol does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 52 targets covered · evidence score 44.2

score 14,005.419

ADRM1ARESR1HIF1ANLRP3PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7+40

Crizotinib

#2 gap-filler · 27 targets covered · evidence score 46.7

score 7,681.055

MAP3K7RIPK2TGFBR1ABL1CSF1RFYNIFNGIKBKBINPPL1IRAK1IRAK3JAK3+15

828 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.