prunetin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARPGRCA1GLUCOCORTICOIDPTPN1USP17L5USP28USP30USP8ALDH2
10 known targets mapped from PubChem bioassay data
Pathway Context
Deubiquitination5 targets overlapping
Ub-specific processing proteases5 targets overlapping
Signaling by Receptor Tyrosine Kinases3 targets overlapping
Uncovered Pathway Targets
259 totalADRB2ADRM1ARRB1BAP1BARD1BRCA1CCNA1CDC25ACDK1CFTR+249 more…
Genes present in the top pathway union that prunetin does not directly modulate.
Top Stack Candidates
Bortezomib
score 14,100.027#1 gap-filler · 51 targets covered · evidence score 44.2
ADRM1ESR1HIF1ANLRP3PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1+39
Sorafenib
score 11,629.878#2 gap-filler · 44 targets covered · evidence score 44.4
CDK1MAP3K7RIPK2TGFBR2AXLBRAFCDK5CSKFGFR1FGFR2FGFR3FLT1+32
751 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.