Puromycin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYTOCHROMECYP3A7SYKTYROSINE-PROTEINNSD2HISTONE-LYSINETP53STK33TOP1P1NPEPPSPUROMYCIN-SENSITIVE
11 known targets mapped from PubChem bioassay data
Pathway Context
Signaling by Interleukins2 targets overlapping
Hemostasis2 targets overlapping
Cell Cycle2 targets overlapping
Uncovered Pathway Targets
351 totalADRM1ALOX15ALOX5ANXA2APPBCL2L1BIRC5CA1CASP1CCL2+341 more…
Genes present in the top pathway union that Puromycin does not directly modulate.
Top Stack Candidates
Bortezomib
score 13,916.534#1 gap-filler · 48 targets covered · evidence score 44.2
ADRM1CA1CREB1CTSGHIF1AIFNGNFKB1NFKB2PSMA1PSMA2PSMA3PSMA4+36
Crizotinib
score 10,668.028#2 gap-filler · 37 targets covered · evidence score 46.7
CSF1RFYNIFNGIKBKBINPPL1IRAK1IRAK3JAK3LCKLYNMAP2K3MAP3K3+25
701 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.