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BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/Resveratrol

Resveratrol — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

ARNR1I2ESR1CYTOCHROMETDP1THRBESRRACYP3A4NFE2L2CHAINGLI3PGRRATTUSRORCMUSNUCLEARTP53RARAEUCHROMATICESR2AHRPPARGPTGS1NTMT1ATAD5NR1H4MAPTSODIUM-DEPENDENTSTK33PTGS2CA1POLKHIF1ACA2CASP3YAP1HDAC9CA7CA12CA4CA5AHTTBRCA1CA5BCA9KCNMB1KCNMB2GFERCA6NFKB1GLSRAPGEF4APPNR5A1NR0B1CA14TRPA1KCNMB4RELAESTROGENIP6K1SENP8CYP1B1MAOBCAR15SMN2TTRAMINEALOX5PHOSPHATIDYLINOSITOLPROSTAGLANDINRAC-ALPHACA3APOBEC3GSRCPLGDPP4NFKB2SENP6CA13SENP7NPC1UBE2NPLAUPLAURSLC2A1PIK3CBNQO2MMP14PRKCAALPGKEAP1FOXO3SGK1SIRT1SLC2A3ALKALINE

97 known targets mapped from PubChem bioassay data

Pathway Context

SUMOylation12 targets overlapping
SUMO E3 ligases SUMOylate target proteins12 targets overlapping
Signaling by Interleukins12 targets overlapping

Uncovered Pathway Targets

198 total
AURKAAURKBBIRC5BLMCREBBPCTBP1DNMT1DNMT3BEIF2AK2EP300+188 more…

Genes present in the top pathway union that Resveratrol does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 42 targets covered · evidence score 44.2

score 12,339.823
HDAC1HDAC2MITFPARP1ADRM1CREB1CTSGIFNGPSMA1PSMA2PSMA3PSMA4+30
Crizotinib

#2 gap-filler · 25 targets covered · evidence score 46.7

score 7,035.182
AURKAAURKBEIF2AK2IKBKENPM1CSF1RFYNIFNGIKBKBINPPL1IRAK1IRAK3+13

617 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.