Rifaximin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
NR1I2SYKTYROSINE-PROTEINNSD2MUSHISTONE-LYSINEDRD3HOMOADRA2BPTGS2DELTA-TYPEADORA1SLC29A1
13 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)2 targets overlapping
Signaling by Interleukins2 targets overlapping
Hemostasis2 targets overlapping
Uncovered Pathway Targets
433 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2CADRB1ADRB2ADRB3+423 more…
Genes present in the top pathway union that Rifaximin does not directly modulate.
Top Stack Candidates
Bortezomib
score 13,581.187#1 gap-filler · 47 targets covered · evidence score 44.2
ADRM1CA1CREB1CTSGHIF1AIFNGNFKB1NFKB2PSMA1PSMA2PSMA3PSMA4+35
Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on
score 10,008.692#2 gap-filler · 35 targets covered · evidence score 44.3
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3DRD2DRD4TSHRCREB1GRK2TAS2R1+23
921 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.