Tamsulosin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
RATTUSKCNH2DRD35-HYDROXYTRYPTAMINEADRA1ADRD2HTR1AADRA2AADRB2HTR2BADRA2CADRA2BMU-TYPEADRB1ADRA1BADRA1DHTR7HTR1BHTR1DGPR151HTR1F
21 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)13 targets overlapping
Amine ligand-binding receptors13 targets overlapping
Adrenoceptors8 targets overlapping
Uncovered Pathway Targets
214 totalADORA2BADORA3ADRB3AGTR1AGTR2APLNRAPPAVPR1AAVPR1BAVPR2+204 more…
Genes present in the top pathway union that Tamsulosin does not directly modulate.
Top Stack Candidates
Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on
score 9,064.392#1 gap-filler · 29 targets covered · evidence score 44.3
ADRB3DRD4TSHRCREB1GRK2TAS2R1TAS2R10TAS2R13TAS2R14TAS2R16TAS2R19TAS2R20+17
Astemizole Antihistamine drug now withdrawn from
score 4,969.935#2 gap-filler · 22 targets covered · evidence score 48.7
APLNRAVPR1ACHRM1CHRM2CHRM3DRD1DRD4GALR2GHSRHRH1HRH2HRH4+10
679 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.