BiohacksAI/Mechanism Hypothesis/Thioinosine Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in
Thioinosine Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19CYP2C9NR1I2TDP1THRBESRRACYP3A7NFE2L2SYKTYROSINE-PROTEINNSD2RORCHISTONE-LYSINENUCLEARTP53AHRNTMT1
17 known targets mapped from PubChem bioassay data
Pathway Context
Biological oxidations4 targets overlapping
Phase I - Functionalization of compounds4 targets overlapping
Cytochrome P450 - arranged by substrate type4 targets overlapping
Uncovered Pathway Targets
84 totalAADACAHCYALDH1A1ALDH2AOC1ARNTCBR3CES1CES2CYP11B1+74 more…
Genes present in the top pathway union that Thioinosine Sulfhydryl analog of INOSINE that inhibits nucleoside transport across erythrocyte plasma membranes, and has immunosuppressive properties. It has been used similarly to MERCAPTOPURINE in does not directly modulate.
Top Stack Candidates
Quercetin
score 3,061.883#1 gap-filler · 16 targets covered · evidence score 43.4
CYP19A1CYP1A1CYP1A2CYP1B1CYP2C8CYP3A4HSP90AB1MAOANNMTRXRAABCB1ABCC1+4
Ritonavir
score 2,860.96#2 gap-filler · 11 targets covered · evidence score 53.4
CYP2B6CYP2D6CYP3A4CYP3A43CYP3A5CYP3A7-CYP3A51PUGT1A1ABCB1SLCO1B1SLCO1B3SLCO2B1
749 more candidates · full stack optimisation locked
Enter your API token to unlock the complete analysis.
BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.