Thiorphan — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ESR1NUCLEARCFTRNNMTPNMTGAMTGNMTHNMTCATECHOLMRGPRX1ACEECE1MME
13 known targets mapped from PubChem bioassay data
Pathway Context
Metabolism of amino acids and derivatives5 targets overlapping
Developmental Cell Lineages4 targets overlapping
Selenoamino acid metabolism3 targets overlapping
Uncovered Pathway Targets
128 totalADRM1AHCYCBSCTHDDCDLDGLSGLULGPT2GSR+118 more…
Genes present in the top pathway union that Thiorphan does not directly modulate.
Top Stack Candidates
Bortezomib
score 12,190.185#1 gap-filler · 42 targets covered · evidence score 44.2
ADRM1PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1PSMB2PSMB3PSMB4+30
Quercetin
score 4,612.028#2 gap-filler · 22 targets covered · evidence score 43.4
GPT2PSMB5TP53ABCG2CA2PGRPLA2G1BPNLIPARCDK1HIF1AOTUD3+10
601 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.