tiopronin — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
PTGS1ALDEHYDEPTGS2ABCC1GNAI1RGS12
6 known targets mapped from PubChem bioassay data
Pathway Context
Fatty acid metabolism2 targets overlapping
Arachidonate metabolism2 targets overlapping
G alpha (i) signalling events2 targets overlapping
Uncovered Pathway Targets
166 totalACAD11AKR1C3ALOX12ALOX15ALOX15BALOX5CBR1CPT2CYP1A1CYP1A2+156 more…
Genes present in the top pathway union that tiopronin does not directly modulate.
Top Stack Candidates
Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on
score 8,851.809#1 gap-filler · 28 targets covered · evidence score 44.3
CREB1DRD3DRD4GRK2TAS2R1TAS2R10TAS2R13TAS2R14TAS2R16TAS2R19TAS2R20TAS2R3+16
Quercetin
score 4,689.11#2 gap-filler · 23 targets covered · evidence score 43.4
ALOX12ALOX15ALOX15BALOX5CYP1A1CYP1A2CYP1B1CYP2C19CYP2C8CYP2C9HPGDPON1+11
806 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.