BiohacksAI/Mechanism Hypothesis/trichostatic acid [Supplementary Concept] related to trichostatin

trichostatic acid [Supplementary Concept] related to trichostatin — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

SYKTYROSINE-PROTEINCHAINNSD2HISTONE-LYSINETP53EUCHROMATICESR2PPARGVDRATAD5CFTRALDEHYDEIFNB1HDAC9GLUCOCORTICOIDHLA-BHDAC6ESTROGENSMN2HDAC10HDAC11HDAC4HDAC5HDAC7HDAC1HDAC2HDAC3HDAC8PROTEINGBA1SIRT6NCOR2HISTONEWNT3ASMN1F3SIRT2NCOR1POLYAMINESF3B3

41 known targets mapped from PubChem bioassay data

Pathway Context

Signaling by NOTCH15 targets overlapping

Signaling by NOTCH113 targets overlapping

NOTCH1 Intracellular Domain Regulates Transcription13 targets overlapping

Uncovered Pathway Targets

66 total

ADAM10ADAM17ADRM1AGO2APH1AAPH1BARRB1ATP2A1ATP2A2ATP2A3+56 more…

Genes present in the top pathway union that trichostatic acid [Supplementary Concept] related to trichostatin does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 36 targets covered · evidence score 44.2

score 11,180.679

ADRM1CREB1ELANEHIF1APSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1+24

Reserpine

#2 gap-filler · 14 targets covered · evidence score 41.7

score 4,022.462

PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1PSMB2PSMB3PSMB4PSMB5+2

215 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.