BiohacksAI/Mechanism Hypothesis/Tubercidin

Tubercidin — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

TDP1RORCNUCLEARABCB1HOMOATXN2CFTRSMAD3MDM2IL1BMDM4IDH1HIF1AYAP1BRCA1PPP1R15AGPR151BARD1NR5A1NR5A2NCOA3HSF1TNFRSF10BEPAS1MELANOCORTINNCOA1NR2F2NCOA2PRNPADKPDCD4

31 known targets mapped from PubChem bioassay data

Pathway Context

Deubiquitination7 targets overlapping

SUMOylation5 targets overlapping

SUMO E3 ligases SUMOylate target proteins5 targets overlapping

Uncovered Pathway Targets

222 total

ADRB2ADRM1ARARRB1BAP1CCNA1CDC25ACDK1EP300ESR1+212 more…

Genes present in the top pathway union that Tubercidin does not directly modulate.

Top Stack Candidates

Bortezomib

#1 gap-filler · 52 targets covered · evidence score 44.2

score 13,821.978

ADRM1ARESR1NLRP3PSMA1PSMA2PSMA3PSMA4PSMA5PSMA6PSMA7PSMB1+40

Quercetin

#2 gap-filler · 42 targets covered · evidence score 43.4

score 8,168.745

ARCDK1ESR1OTUD3POLBPSMB5SMAD2TP53UCHL1USP10USP17L5USP28+30

870 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.