BiohacksAI/Mechanism Hypothesis/17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as

17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6ARCYP2C9NR1I2ESR1CYTOCHROMETDP1THRBESRRACYP3A4CYP3A7NFE2L2PGRNSD2RORCHISTONE-LYSINENUCLEARNR3C1KCNH2RARAESR2CYP19A1TSHRATXN2ABCB11HSPB1NPSR1KCNQ1KCNQ2KCNK3POTASSIUM

32 known targets mapped from PubChem bioassay data

Pathway Context

Nuclear Receptor transcription pathway8 targets overlapping

Biological oxidations6 targets overlapping

Phase I - Functionalization of compounds6 targets overlapping

Uncovered Pathway Targets

119 total

ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2NR1H2+109 more…

Genes present in the top pathway union that 17 alpha-Hydroxyprogesterone Caproate Hydroxyprogesterone derivative that acts as does not directly modulate.

Top Stack Candidates

Progesterone

#1 gap-filler · 16 targets covered · evidence score 50.6

score 4,189.664

ESRRGHNF4AHNF4GNR1H2NR1H4NR2F1NR3C2NR4A2NR5A1NR5A2RARBRARG+4

Luteolin 5,7,3',4'-tetrahydroxy-flavone,

#2 gap-filler · 16 targets covered · evidence score 40.6

score 3,262.846

NR1H2NR1H3PPARGCBR3CYP1A1CYP1A2CYP1B1GSTO1MAOAAURKBBLMNFKB2+4

590 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.