BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
BiohacksAI is an evolving scientific literature platform. New compounds and evidence are indexed continuously.
B

Progesterone

The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.

496+ PubMed studies analyzed · 64 RCTs · Evidence Score: 60.4

Research Domains

Progesterone has been studied across 15 research domains including 🧬 Hormones, 😴 Sleep, ♀♂ Sexual Health, 🔬 Oncology, 🧠 Focus & Attention. The primary research focus is 🧬 Hormones with 90% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Progesterone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Testosterone
30 shared targets
Spironolactone
26 shared targets
Dihydrotestosterone
25 shared targets
Ethinyl
30 shared targets
Medroxyprogesterone
23 shared targets
Danazol
25 shared targets
Corticosterone
20 shared targets
Norethindrone
20 shared targets
Flutamide
24 shared targets
Gestrinone
21 shared targets
Loading evidence profile...

This evidence profile for Progesterone is generated deterministically from 496 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.