Abiraterone Acetate — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ESR1THRBPGRRATTUSCYP17A1STEROID
6 known targets mapped from PubChem bioassay data
Pathway Context
SUMOylation2 targets overlapping
SUMO E3 ligases SUMOylate target proteins2 targets overlapping
Nuclear Receptor transcription pathway2 targets overlapping
Uncovered Pathway Targets
129 totalARAURKAAURKBBIRC5BLMBRCA1CREBBPCTBP1DNMT1DNMT3B+119 more…
Genes present in the top pathway union that Abiraterone Acetate does not directly modulate.
Top Stack Candidates
Progesterone
score 5,074.7#1 gap-filler · 22 targets covered · evidence score 50.6
ARNR1H2NR1H4NR1I2NR3C1NR3C2NR4A2NR5A1NR5A2RARARORARXRA+10
Quercetin
score 4,234.188#2 gap-filler · 22 targets covered · evidence score 43.4
ARAURKBBLMNFKB2NR1I2NR3C1PPARGRELARXRATOP1TOP2ATP53+10
674 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.