Alprenolol — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2D6CYP1A2KCNH25-HYDROXYTRYPTAMINEADRA1AHTR1AADRB2ADRB1ADRB3FDFT1
10 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)5 targets overlapping
Amine ligand-binding receptors5 targets overlapping
Adrenoceptors4 targets overlapping
Uncovered Pathway Targets
228 totalADORA2BADORA3ADRA1BADRA1DADRA2AADRA2BADRA2CAGTR1AGTR2APLNR+218 more…
Genes present in the top pathway union that Alprenolol does not directly modulate.
Top Stack Candidates
Fluoxetine
score 6,843.156#1 gap-filler · 24 targets covered · evidence score 73.4
ADRA1BADRA1DADRA2AADRA2BADRA2CCCKBRCHRM3CHRM5CNR1DRD1DRD2EDNRA+12
Astemizole Antihistamine drug now withdrawn from
score 6,647.826#2 gap-filler · 33 targets covered · evidence score 48.7
ADRA2AADRA2CAPLNRAVPR1ACHRM1CHRM2CHRM3DRD1DRD2DRD3DRD4GALR2+21
932 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.