BETABiohacksAI is a research tool for informational purposes only. All outputs are computational hypothesis candidates — not confirmed mechanisms, not medical advice, and not a substitute for professional medical judgment. Independent experimental validation is always required.
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Fluoxetine

The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.

1.0k+ PubMed studies analyzed · 543 RCTs · Evidence Score: 75.8

Research Domains

Fluoxetine has been studied across 17 research domains including 🌤️ Mood & Depression, 😴 Sleep, 🧘 Stress & Anxiety, ❤️ Cardiovascular, 🧠 Cognitive. The primary research focus is 🌤️ Mood & Depression with 69% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Fluoxetine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

risperidone
22 shared targets
Cabergoline
21 shared targets
brexpiprazole
21 shared targets
clozapine
22 shared targets
clemastine
20 shared targets
Mianserin
29 shared targets
Maprotiline
28 shared targets
Cyproheptadine
31 shared targets
Aripiprazole
32 shared targets
clomipramine
19 shared targets
Loading evidence profile...

This evidence profile for Fluoxetine is generated deterministically from 1,001 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.