Beclomethasone — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19CYP2D6ARCYP2C9NR1I2CYTOCHROMEESRRACYP3A4CYP3A7SYKTYROSINE-PROTEINPGRNSD2HISTONE-LYSINENUCLEARNR3C1HOMOESR2CFTRIL1BHIF1AGLUCOCORTICOIDRXFP1
23 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway6 targets overlapping
Biological oxidations5 targets overlapping
Phase I - Functionalization of compounds5 targets overlapping
Uncovered Pathway Targets
86 totalESR1ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2+76 more…
Genes present in the top pathway union that Beclomethasone does not directly modulate.
Top Stack Candidates
Progesterone
score 4,306.998#1 gap-filler · 17 targets covered · evidence score 50.6
ESR1ESRRGHNF4AHNF4GNR1H2NR1H4NR2F1NR3C2NR4A2NR5A1NR5A2RARA+5
Gemfibrozil
score 3,267.311#2 gap-filler · 13 targets covered · evidence score 51.5
NR1H2NR2F1NR5A1NR5A2PPARARARARARBRARGRORARXRAAHRCYP1A2+1
612 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.