Benzydamine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2D6CYP1A2SYKTYROSINE-PROTEINNSD2HISTONE-LYSINEKCNH2CHRM1DRD3HOMODRD1HTR1AADRA2ASLC6A3SLC6A4SLC6A2CHRM2GPT2GUANYLATEGUCY1A1GUCY1A2GUCY1B1
22 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)6 targets overlapping
Amine ligand-binding receptors6 targets overlapping
Hemostasis5 targets overlapping
Uncovered Pathway Targets
406 totalADORA2BADORA3ADRA1AADRA1BADRA1DADRA2BADRA2CADRB1ADRB2ADRB3+396 more…
Genes present in the top pathway union that Benzydamine does not directly modulate.
Top Stack Candidates
Astemizole Antihistamine drug now withdrawn from
score 7,986.983#1 gap-filler · 36 targets covered · evidence score 48.7
ADRA1AADRA2CADRB2APLNRAVPR1ACHRM3DRD2DRD4GALR2GHSRHRH1HRH2+24
Aripiprazole
score 7,937.812#2 gap-filler · 35 targets covered · evidence score 52.0
ADORA3ADRA1AADRA1BADRA1DADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AVPR1ADRD2+23
876 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.