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BiohacksAI

Evidence-Based Biohacking

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BiohacksAI/Mechanism Hypothesis/Butaclamol

Butaclamol — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

RATTUSCHRM1DRD35-HYDROXYTRYPTAMINEDRD2DRD1CHRM2CHRM5CHRM4CHRM3HTR7DRD4SIGMAR1DRD5

14 known targets mapped from PubChem bioassay data

Pathway Context

Amine ligand-binding receptors11 targets overlapping
Dopamine receptors5 targets overlapping

Uncovered Pathway Targets

201 total
ADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2+191 more…

Genes present in the top pathway union that Butaclamol does not directly modulate.

Top Stack Candidates

Isoproterenol Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on

#1 gap-filler · 33 targets covered · evidence score 44.3

score 9,688.939
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3TSHRCREB1GRK2TAS2R1TAS2R10TAS2R13+21
Aripiprazole

#2 gap-filler · 26 targets covered · evidence score 52.0

score 5,580.571
ADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1AVPR1A+14

654 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.