Chlorpheniramine — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
MUSKCNH2CHRM15-HYDROXYTRYPTAMINEADRA1AHTR2BADRA2BSLC6A3SLC6A4SLC6A2CHRM2HRH1CHRM5HRH2SCN2ASCN3ASCN1A
17 known targets mapped from PubChem bioassay data
Pathway Context
Class A/1 (Rhodopsin-like receptors)8 targets overlapping
Amine ligand-binding receptors8 targets overlapping
G alpha (q) signalling events5 targets overlapping
Uncovered Pathway Targets
223 totalADORA2BADORA3ADRA1BADRA1DADRA2AADRA2CADRB1ADRB2ADRB3AGTR1+213 more…
Genes present in the top pathway union that Chlorpheniramine does not directly modulate.
Top Stack Candidates
Astemizole Antihistamine drug now withdrawn from
score 6,109.08#1 gap-filler · 28 targets covered · evidence score 48.7
ADRA2AADRA2CADRB2APLNRAVPR1ACHRM3DRD1DRD2DRD3DRD4GALR2GHSR+16
Aripiprazole
score 5,814.436#2 gap-filler · 27 targets covered · evidence score 52.0
ADORA3ADRA1BADRA1DADRA2AADRA2CADRB1ADRB2ADRB3AGTR1AVPR1ADRD1DRD2+15
695 more candidates · full stack optimisation locked
Enter your API token to unlock the complete analysis.
BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.