BiohacksAI/Mechanism Hypothesis/Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of

Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

ESR1CYP3A4NFE2L2RORCABCB1EUCHROMATICIFNGVDRMAPTGMNNALOX15GLRA1GC

13 known targets mapped from PubChem bioassay data

Pathway Context

Drug ADME2 targets overlapping

SUMOylation2 targets overlapping

SUMO E3 ligases SUMOylate target proteins2 targets overlapping

Uncovered Pathway Targets

110 total

ABCC1ABCC2ABCC3ABCC4ABCC5ABCG2ADAADKAKR1C1ALB+100 more…

Genes present in the top pathway union that Cholecalciferol Derivative of 7-dehydroxycholesterol formed by ULTRAVIOLET RAYS breaking of does not directly modulate.

Top Stack Candidates

Quercetin

#1 gap-filler · 27 targets covered · evidence score 43.4

score 4,853.593

ABCC1ABCG2CYP2C19CYP2C8CYP2C9PON1SLCO2B1XDHARAURKBBLMNFKB2+15

Progesterone

#2 gap-filler · 21 targets covered · evidence score 50.6

score 3,929.846

CYP2C19CYP2C9CYP2D6SERPINA6SLC22A1SLC22A3ARNR1H2NR1H4NR1I2NR3C1NR3C2+9

867 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.