Desogestrel — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
ARNR1I2ESR1THRBPGRNR3C1DRD3SLC6A4SLC6A2GMNNCHRM2ANDROGENADORA3SHBG
14 known targets mapped from PubChem bioassay data
Pathway Context
SUMOylation5 targets overlapping
SUMO E3 ligases SUMOylate target proteins5 targets overlapping
Nuclear Receptor transcription pathway5 targets overlapping
Uncovered Pathway Targets
217 totalAURKAAURKBBIRC5BLMBRCA1CREBBPCTBP1DNMT1DNMT3BEIF2AK2+207 more…
Genes present in the top pathway union that Desogestrel does not directly modulate.
Top Stack Candidates
Astemizole Antihistamine drug now withdrawn from
score 7,293.987#1 gap-filler · 37 targets covered · evidence score 48.7
BRCA1MDM2MITFPPARGRARATP53ESR2ESRRAPPARDADRA1AADRA2AADRA2C+25
Fluoxetine
score 6,913.997#2 gap-filler · 24 targets covered · evidence score 73.4
RARAESR2ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CCCKBRCHRM3CHRM5CNR1+12
859 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.