Desoxycorticosterone — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19ARCYP2C9NR1I2ESR1TDP1THRBESRRACYP3A7GLI3PGRRORCNR3C1ABCB1RARADRD3IFNGJUNSHBGGNRHRSERPINA6SLC22A2NR3C2PLGSLC22A3PLAUPLAUR
27 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway8 targets overlapping
SUMOylation7 targets overlapping
SUMO E3 ligases SUMOylate target proteins7 targets overlapping
Uncovered Pathway Targets
113 totalESR2ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2+103 more…
Genes present in the top pathway union that Desoxycorticosterone does not directly modulate.
Top Stack Candidates
Progesterone
score 4,316.453#1 gap-filler · 17 targets covered · evidence score 50.6
ESR2ESRRGHNF4AHNF4GNR1H2NR1H4NR2F1NR4A2NR5A1NR5A2RARBRARG+5
Gemfibrozil
score 3,536.897#2 gap-filler · 13 targets covered · evidence score 51.5
NR1H2NR2F1NR5A1NR5A2PPARARARBRARGRORARXRAABCC2CYP2C8SLCO1B1+1
714 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.