Desoxycorticosterone Acetate — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19ARCYP2C9ESR1THRBESRRACYP3A7GLI3PGRNR3C1ABCB1RARAIFNGCHRM4ANO1
15 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway6 targets overlapping
SUMOylation5 targets overlapping
SUMO E3 ligases SUMOylate target proteins5 targets overlapping
Uncovered Pathway Targets
124 totalESR2ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2+114 more…
Genes present in the top pathway union that Desoxycorticosterone Acetate does not directly modulate.
Top Stack Candidates
Bortezomib
score 12,440.522#1 gap-filler · 43 targets covered · evidence score 44.2
ESR2NR1I2PPARDHDAC1HDAC2MITFNFKB2PARP1RELATP53ADRM1HDAC3+31
Progesterone
score 4,572.258#2 gap-filler · 18 targets covered · evidence score 50.6
ESR2ESRRGHNF4AHNF4GNR1H2NR1H4NR1I2NR2F1NR3C2NR4A2NR5A1NR5A2+6
561 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.