Dydrogesterone — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19CYP2D6ARCYP2C9NR1I2TDP1THRBESRRACYP3A7NFE2L2GLI3PGRNSD2HISTONE-LYSINENR3C1CHRM1ANDROGEN
17 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway5 targets overlapping
Biological oxidations4 targets overlapping
Phase I - Functionalization of compounds4 targets overlapping
Uncovered Pathway Targets
124 totalESR1ESR2ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1+114 more…
Genes present in the top pathway union that Dydrogesterone does not directly modulate.
Top Stack Candidates
Progesterone
score 4,598.132#1 gap-filler · 19 targets covered · evidence score 50.6
ESR1ESR2ESRRGHNF4AHNF4GNR1H2NR1H4NR2F1NR3C2NR4A2NR5A1NR5A2+7
Quercetin
score 3,558.482#2 gap-filler · 20 targets covered · evidence score 43.4
ESR1PPARGRXRAAHRCYP19A1CYP1A1CYP1A2CYP1B1CYP2C8CYP3A4HSP90AB1MAOA+8
717 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.