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BiohacksAI

Evidence-Based Biohacking

Patent Pending
BiohacksAI/Mechanism Hypothesis/Ethinyl Estradiol

Ethinyl Estradiol — Mechanism Gap Analysis

HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal

Known Targets

CYP2C19CYP2D6ARCYP2C9NR1I2ESR1CYTOCHROMETDP1CYP1A2THRBESRRACYP3A4CYP3A7SYKTYROSINE-PROTEINGLI3PGRRATTUSNSD2RORCHISTONE-LYSINENUCLEARTP53NR3C1ABCB1RARAHTR2AESR2HTR1AIFNGTSHRNTMT1SLC6A3PMP22SLC6A4NR1H4SLC6A2SMAD3GMNNSODIUM-DEPENDENTSMAD2ANDROGENABCB11IDH1CREB1CASP3GLUCOCORTICOIDPPARDHSPB1SHBGCASP7KCNMB2ESTROGENNLRP3KCNQ1SLC22A2LRRC26NR1I3CXCL8CASP1UGT1A1NLRP1CYP2B6SULT1A1AOX1

65 known targets mapped from PubChem bioassay data

Pathway Context

Nuclear Receptor transcription pathway11 targets overlapping
Biological oxidations9 targets overlapping
Phase I - Functionalization of compounds8 targets overlapping

Uncovered Pathway Targets

113 total
ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2NR1H2+103 more…

Genes present in the top pathway union that Ethinyl Estradiol does not directly modulate.

Top Stack Candidates

Progesterone

#1 gap-filler · 13 targets covered · evidence score 50.6

score 3,754.962
ESRRGHNF4AHNF4GNR1H2NR2F1NR3C2NR4A2NR5A1NR5A2RARBRARGRORA+1
Luteolin 5,7,3',4'-tetrahydroxy-flavone,

#2 gap-filler · 16 targets covered · evidence score 40.6

score 3,295.858
NR1H2NR1H3PPARGCBR3CYP19A1CYP1A1CYP1B1GSTO1MAOAAURKBBLMNFKB2+4

461 more candidates · full stack optimisation locked

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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.