Finasteride — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19CYP2D6ARCYP2C9NR1I2ESR1CYTOCHROMETHRBESRRANFE2L2GLI3RATTUSRORCMUSRARAHOMONR1H4SRD5A1SRD5A2
19 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway6 targets overlapping
SUMOylation5 targets overlapping
SUMO E3 ligases SUMOylate target proteins5 targets overlapping
Uncovered Pathway Targets
124 totalESR2ESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR0B1NR1D1NR1D2+114 more…
Genes present in the top pathway union that Finasteride does not directly modulate.
Top Stack Candidates
Progesterone
score 4,427.127#1 gap-filler · 18 targets covered · evidence score 50.6
ESR2ESRRGHNF4AHNF4GNR1H2NR2F1NR3C1NR3C2NR4A2NR5A1NR5A2PGR+6
Quercetin
score 3,689.604#2 gap-filler · 21 targets covered · evidence score 43.4
NR3C1PGRPPARGRXRAAURKBBLMNFKB2RELATOP1TOP2ATP53AHR+9
728 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.