fluoranthene — Mechanism Gap Analysis
HYPOTHESIS_ENGINE_v1.0 · Corpus v20260227-01 · Deterministic graph-traversal
Known Targets
CYP2C19ARNR1I2ESR1CYP1A2NFE2L2CHAINPGRNUCLEARNR0B1ATF6
11 known targets mapped from PubChem bioassay data
Pathway Context
Nuclear Receptor transcription pathway5 targets overlapping
SUMOylation4 targets overlapping
SUMO E3 ligases SUMOylate target proteins4 targets overlapping
Uncovered Pathway Targets
126 totalESR2ESRRAESRRBESRRGHNF4AHNF4GNCOR1NCOR2NR1D1NR1D2+116 more…
Genes present in the top pathway union that fluoranthene does not directly modulate.
Top Stack Candidates
Progesterone
score 4,828.293#1 gap-filler · 21 targets covered · evidence score 50.6
ESR2ESRRAESRRGHNF4AHNF4GNR1H2NR1H4NR2F1NR3C1NR3C2NR4A2NR5A1+9
Quercetin
score 3,670.851#2 gap-filler · 21 targets covered · evidence score 43.4
ESRRANR3C1PPARGRXRAAURKBBLMNFKB2RELATOP1TOP2ATP53AHR+9
766 more candidates · full stack optimisation locked
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BiohacksAI maps biological mechanisms. It does not recommend compounds. Results generated by HYPOTHESIS_ENGINE_v1.0.